Call for Papers for a Special Issue of the Neurobiology of Disease: Metabolic Disorders and Neurodegeneration
Editors: Radosveta Koldamova and Iliya Lefterov
Understanding the risk for development and molecular pathogenesis of neurodegenerative disorders is both important and challenging. Important because this is one way to identify a combination of environmental and systemic factors that can rationalize and substantiate preventive strategies and new therapeutic approaches. Challenging because of the complexity of a group of diseases with unknown length of prodromal period and certainly not fully understood critical physiological and metabolic disturbances in the periphery. The challenge is hard to meet and perhaps because of its multidisciplinary nature, there is no single resource that collects cutting edge work in a field of human pathology - neurodegeneration, with enormous multifaceted impact on individual families and the entire society.
For these reasons, the Editorial Board of Neurobiology of Disease plans a special issue entitled “Metabolic Disorders and Neurodegeneration”. The scope of the issue is intended to be broad, and consisting of reviews:
• Focused on epidemiology of neurodegenerative disorders, specifically the role of perturbed metabolism, (diabetes, dyslipidemia, obesity, metabolic syndrome);
• Emphasizing the specifics and common aspects of lipid and lipoprotein metabolism in periphery and brain in the context of AD and other neurodegenerative disorders;
• Presenting the current knowledge of the transcriptional regulation, epigenetic modifications of genes involved in carbohydrate and lipid metabolism and the role of noncoding RNAs in Alzheimer's disease and other neurodegenerative disorders;
• Describing the role of perturbed mitochondrial metabolism and catabolic processes in the pathogenesis of neurodegeneration;
• Addressing the impact of lifestyle and particularly diet, exercise and sleep on the risk and development of neurodegeneration;
• Presenting the latest diagnostic strategies in neuroimaging for early diagnosis of sporadic AD, based on changes in brain metabolism.
The above topics of the focused reviews in the special issue are examples, not an exclusive list. Prospective authors are encouraged to contact one of the editors (Dr. Radosveta Koldamova, firstname.lastname@example.org or Dr. Iliya Lefterov, email@example.com) prior to preparing a submission.
The papers should be submitted for review by the end of January 2014 with a plan for publication in the spring of 2014. To submit to the Special Issue visit the Submission site of Neurobiology of Disease and select the Special Issue (short title for internal use, “Metabolism/Neurodegeneration”) when submitting your paper.